Categorized Under: Environment
ICF is supporting EPA in analyzing human health risks associated with exposure to 2,3,7,8-TCDD in order to develop a response to comments from the National Academy of Sciences on EPA's 2003 reassessment of health risks from dioxins and related compounds.
This support includes reviewing and analyzing available epidemiologic and animal bioassay data, performing dose-response modeling, refining and applying physiologically based pharmacokinetic (PBPK) models, and developing an oral cancer slope factor and reference dose (RfD) for 2,3,7,8-TCDD.
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